科研項目 1. 山西省教育廳教改項目,J20230518,“金課”視域下《藥物化學》混合式教學模式的研究與實踐,2023/05-2025/05,1.0萬元,在研,主持。 2. 山西醫(yī)科大學校級教改項目,XJ2018064,《藥用化學》教學改革與實踐探索,2018/01-2019/12,0.3萬元,結(jié)題,主持。 3. 山西省科技廳青年基金項目,20210302124586,黃芪注射液中植物初級代謝物的作用研究,2022/01-2024/12,4萬,在研,主持。 4. 山西省科技廳重點研發(fā)項目,氯法齊明工藝改進與短療程治療多耐藥肺結(jié) 核新適應癥關(guān)鍵技術(shù)研究,2022/01-2025/01,8.0萬元,合作單位第一負責人。 5. 太原市科技局太原市關(guān)鍵核心技術(shù)攻關(guān)“揭榜掛帥”項目,心腦血管藥物舒血寧注射液高純化原料分離和質(zhì)量精準控制關(guān)鍵技術(shù)攻關(guān),2023/06-2025/12,60.0萬元,揭榜單位第一負責人。 發(fā)表論文 (1) Xiaolin Lu, Liqiu Yan, Xiaoxue Zhou, Tingli Qu*.Highly selective colorimetric determination of glutathione based on sandwich?structured nanoenzymes composed of gold nanoparticle–coated molecular imprinted metal-organic frameworks. Microchimica Acta, 2024, 191:140. https://doi.org/10.1007/s00604-023-06167-2(2區(qū),IF=5.700) (2) Liqiu Yan, Fangfang Liu, Yanyang Zhang, Erbing Wang &Tingli Qu*. Elucidating the active ingredients and potential anti-inflammatory mechanism of Qingwei Huanglian Wan. Journal of Liquid Chromatography & Related Technologies, 2023, DOI: 10.1080/10826076.2023.2297950.(4區(qū),IF=1.300) (3) Tingli Qu, Yao Gao, Aiping Li, Zhenyu Li*, and Xuemei Qin*. Systems biology analysis of the effect and mechanism of total flavonoids of Astragali Radix against cyclophosphamide-induced leucopenia in mice. Journal of Pharmaceutical and Biomedical Analysis, 2021, 205: 114357.(3區(qū),IF=3.935) (4) Erbing Wang, Teng Liu, Xiaolin Lu, Jinfang Xu, Qian Zheng, ZhengbaoZhao*, andTingli Qu*. Comparison of aerial parts of Astragalusmembranaceus and Astragali Radix based onchemical constituents and pharmacological effects. Food and Agricultural Immunology, 2019, 30(1): 1046-1066.(2區(qū),IF=2.398) (5) Tingli Qu, Erbing Wang, Baofen Jin, Weiping Li, Ruiling Liu, and Zhengbao Zhao*. 5-Aminosalicylic acid inhibits inflammatory responses by suppressing JNK andp38 activity in murine macrophages. Immunopharmacology and Immunotoxicology, 2017,39(1): 45-53.(4區(qū),IF=2.086) (6) Tingli Qu, Erbing Wang, Aiping Li, Guanhua Du, Zhenyu Li*, and Xuemei Qin*. NMR based metabolomic approach revealed cyclophosphamide-induced systematic alterations in a rat model. RSC Advances, 2016, 6(112): 111020-111030. (2區(qū),IF=3.328) (7) Tingli Qu, Zhenyu Li*, Sijun Zhao, Aiping Li, and Xuemei Qin*. A metabonomic analysis reveals novel regulatory mechanism of Huangqi injection on leucopenia mice, Immunopharmacology and Immunotoxicology, 2016, 38(2): 113-123. (4區(qū),IF=2.086) 申請專利 (1)發(fā)明名稱:一種黃芪注射液1H-NMR指紋圖譜的構(gòu)建方法;發(fā)明人:李震宇,曲婷麗,張麗增,張松,秦雪梅;專利號:ZL 201410446123.8。 (2)發(fā)明名稱:一種用于止嗽定喘祛痰的中藥口服制劑;發(fā)明人:趙正保,曲婷麗,張西成,侯文林;專利號:ZL 200710163953.X。 (3)實用新型:一種中藥提取裝置;發(fā)明人:王二兵,曲婷麗;專利號:CN208212576U。 |